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KMID : 0870420070110040041
Korean Journal of Hepato-Biliary-Pancreatic Surgery
2007 Volume.11 No. 4 p.41 ~ p.46
Clinical Analysis of Focal Nodular Hyperplasia of the Liver in 11 Patients
Song Kee-Ho

Suh Kyung-Suk
Lee Kuhn-Uk
Yi Nam-Joon
Park Kwi-Won
Shin Woo-Young
Lee Hae-Won
Kim Ju-Hyun
Abstract
Purpose: The purpose of this study was to determine the clinical features of focal nodular hyperplasia (FNH) and investigate its diagnosis and treatment.

Methods: Eleven patients with FNH treated from January 1997 to January 2007 were analyzed. The clinical findings of pathologically proven FNH were retrospectively reviewed.

Results: Among the eleven patients with 18 masses, the mean age was 29.5 (11~57) and the gender ratio (male:female) was 4:7. Four patients had clinical symptoms. Six patients had a solitary mass and five had multiple masses. The mean tumor diameter was 2.73 +/- 1.82 cm. The overall rate of a correct preoperative diagnosis was 0% (0/4) by ultrasound, 36.3% (4/11) by CT and 20.0% (2/10) by MRI. Only two patients had a central stellate scar in the mass. All patients underwent hepatic resection without complication.

Conclusion: The results of this study showed that the combination of Dynamic CT and dual contrast MRI are important diagnostic methods for FNH. However, a definite preoperative diagnosis of FNH, without a central stellate scar, is very difficult. Surgical resection is recommended for patients with an uncertain diagnosis or clinical symptoms.
KEYWORD
Liver, Focal nodular hyperplasia, Benign hepatic tumor
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